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Protexin Veterinary Pro-Kolin Advanced Paste for Dogs is an easy-to-give, tasty, liver-flavoured paste that supports gut health, soothes the gut lining, firms up faeces and supports the immune system. Made with Petbiotix®, a combination of prebiotics and probiotics to support a healthy microbiome and good gut health.
Easy-to-give, artificial liver-flavoured paste
With a highly palatable flavour your dog will love and a handy dosage wheel on our syringe plunger, it’s simple to make sure they get the right amount up to three times daily.
Smarter, biotic-powered pet care for a healthier gut
Protexin Veterinary Pro-Kolin Advanced Paste for Dogs contains the probiotic Enterococcus faecium (DSM 10663/NCIMB 10415) 4b1707, which helps promote good bacteria in their gut microbiome. It also contains the prebiotic Preplex, which feeds these good bacteria, and Pectin, which soothes the gut lining.
Fibre for firmer, regular poops
Psyllium, a soluble dietary fibre, regulates intestinal transit time and, alongside the natural binding agents Kaolin and Montmorillonite, helps firm up faeces.
Extra ingredients for added immunity support
Protexin Veterinary Pro-Kolin Advanced Paste for Dogs also contain beta-glucans to support a healthy immune system.
Pro-Kolin Advanced For Dogs Contains
Pro-Kolin Advanced is a highly palatable paste which is available in 15ml, 30ml and 60ml syringes with easy to read graduations, making the product easy to administer.
Directions For Use
Pro-Kolin Advanced is a highly palatable paste which is available in 15ml, 30ml and 60ml syringes with easy to read graduations, making the product easy to administer.
We recommend using 15ml and 30ml syringes for small to medium dogs but also in a handy 60ml syringe for larger dogs.
Give by mouth for as long as considered necessary or as advised by your veterinary surgeon.
Pro-Kolin Advanced can be given up to three times daily, depending on severity.
Pro-Kolin Advanced For Dogs 15ml and 30ml:
| Weight | Volume | Frequency |
| <5kg | 2ml | Twice daily |
| 5-15kg | 3ml | Twice daily |
| 15-30kg | 5ml | Twice daily |
| >30kg | 7ml | Twice daily |
Pro-Kolin Advanced For 60ml – same formulation as 15ml and 30ml preparations but in a handy syringe for larger dogs
| Weight | Volume | Frequency |
| 25-35kg | 6ml | Twice daily |
| 35-45kg | 8ml | Twice daily |
| >45kg | 10ml | Twice daily |
Pro-Kolin Advanced can be given up to three times daily, depending on severity.
To administer the correct amount of the product use the handy wheel on the syringe plunger. Rotate the wheel until it is to the right of the number representing the desired quantity to be administered (see diagram below showing the correct and incorrect position for 10ml).

Pro-Kolin Advanced Contains
Additives
Gut Flora Stabilisers
Protexin probiotic
Enterococcus faecium (DSM 10663/ NCIMB 10415) 4b1707
2 x 1011 CFU/kg; 2 x 108 CFU/g
Technological Additives
Bentonite montmorillonite, Preplex® prebiotic – Acacia (Gum arabic), Kaolin
Sensory Additives
Artificial liver flavouring
Composition
Soya oil, Psyllium husk, Pectin, Preplex® prebiotic (Fructo-oligosaccharide), Beta-glucans, Dextrose
What is the difference between Pro-Kolin+ and Pro-Kolin Advanced?
Pro-Kolin Advanced contains the same high quality ingredients as the original Pro-Kolin, but also contains a few extra ingredients to further support the gastrointestinal tract. These extra ingredients include another clay, montmorillonite, fibre in the form of psyllium and also beta-glucans. In addition to this, Pro-Kolin Advanced is now available as separate products for dogs and cats with different flavourings to please the most discerning canines and felines.
Storage
Pro-Kolin Advanced has a 2 year shelf life from the date of manufacture. Once open replace the lid securely and store in a cool dry area. Stored correctly Pro-Kolin Advanced will last until the Best Before End date even if it has been opened.
Protexin Veterinary Pro-Kolin Advanced Paste for Cats is an easy-to-give, tasty, chicken-flavoured paste that supports gut health, soothes the gut lining, firms up runny poos and supports the immune system. Made with Petbiotix®, a combination of prebiotics, probiotics and postbiotics, to support a healthy microbiome and good gut health
Easy-to-give, tasty, artificial chicken-flavoured paste
With a highly palatable flavour your cat will love and a handy dosage wheel on our syringe plunger, it’s simple to give the the right amount up to three times daily.
Smarter, biotic-powered pet care for a healthier gut
Protexin Veterinary Pro-Kolin Advanced Paste for Cats contains the probiotic Enterococcus faecium (DSM 10663/NCIMB 10415) 4b1707, which helps promote good bacteria in their gut microbiome. It also contains the prebiotic Preplex®, a combination of oligofructose
(FOS) and acacia (gum arabic), which supports the growth of good bacteria, and Pectin, to soothe the gut lining.
Fibre for firmer, regular poops
Psyllium, a soluble dietary fibre, promotes intestinal transit time and, alongside the natural binding agents Kaolin and Montmorillonite, helps firm up faeces.
Extra ingredients for added immunity support
Protexin Veterinary Pro-Kolin Advanced Paste for Cats also contains beta-glucans to support a healthy immune system and the essential amino acid for cats, taurine, which is necessary to support many normal processes including vision, digestion, heart health and immune system.
Pro-Kolin Advanced For Cats Contains
Pro-Kolin Advanced is a highly palatable paste which is available in 15ml syringe with easy to read graduations, making the product easy to administer.
Directions For Use
Give by mouth for as long as considered necessary or as advised by your veterinary surgeon.
Pro-Kolin Advanced For Cats 15ml :
| Weight | Volume | Frequency |
| <5kg | 2ml | Twice daily |
| 5-15kg | 3ml | Twice daily |
| 15-30kg | 5ml | Twice daily |
| >30kg | 7ml | Twice daily |
Pro-Kolin Advanced Cats can be given up to three times daily, depending on severity.
To administer the correct amount of the product use the handy wheel on the syringe plunger. Rotate the wheel until it is to the right of the number representing the desired quantity to be administered (see diagram below showing the correct and incorrect position for 10ml).

Additives
Gut Flora Stabilisers
Protexin probiotic
Enterococcus faecium (DSM 10663/ NCIMB 10415) 4b1707
2 x 1011 CFU/kg; 2 x 108 CFU/g
Technological Additives
Bentonite montmorillonite, Preplex® prebiotic – Acacia (Gum arabic), Kaolin
Sensory Additives
Artificial chicken flavouring for cats
Nutritional Additives
Taurine
Composition
Soya oil, Psyllium husk, Pectin, Preplex® prebiotic (Fructo-oligosaccharide), Beta-glucans, Dextrose
Technological Additives
Bentonite montmorillonite, Preplex® prebiotic – Acacia (Gum arabic), Kaolin
Sensory Additives
Artificial chicken flavouring for cats
Nutritional Additives
Taurine
Composition
Soya oil, Psyllium husk, Pectin, Preplex® prebiotic (Fructo-oligosaccharide), Beta-glucans, Dextrose
Pro-Kolin Advanced has a 2 year shelf life from the date of manufacture. Once open replace the lid securely and store in a cool dry area. Stored correctly Pro-Kolin Advanced will last until the Best Before End date even if it has been opened.
All prices include VAT where applicable.
| Overall | |
| Effectiveness | |
| Ease Of Use | |
| Value For Money | |
| Absence Of Side Effects |
Only verified purchasers of this product can leave a review.
Seems to be working
Customer recommends this product
It's a very good product measured dose is easy to do.My dogs gut improvement is great
Customer recommends this product
Excellent quick-acting product to have as a stand-by in case of stomach issues. Always take some along when away from home too.
Customer recommends this product
Anybody who has a dog with a digestive system that is sensitive will appreciate this paste. It was prescribed by the vet when our English bulldog was a puppy and it works so well. Since then we keep a tube of it in the fridge just in case. When she needs it we mix a dose in with her food and it must taste ok because she eats it up. It is worth every penny .
Customer recommends this product
My dog was seriously ill having eaten something she shouldn't. And by the time I was aware, it was too late for the vet to administer the injection to empty her stomach - besides, that injection has no effect on my dog 🙈 she's just quirky like that. This product helped her recover and settle her intestines from quite a scary prolonged episode. Highly recommend.
Customer recommends this product
Below are some recent questions we've received regarding Protexin Veterinary Pro-Kolin Advanced Gut Health Paste, including answers from our team.
Annie
Can I use prokolin with my diabetic dog with diarrhea?
As you are already under the direction of a vet, unfortunately we are unable to provide any further advice. We would suggest that you contact your vet on this occasion as they already have a treatment plan set out for you.
Graham Rates
My dog is already taking Pre and Pro digestive pills but still has regular very runny' anal discharge. How can I firm this up.
I would advise contacting your vet on this occasion for a health check on your dog and to ask for their advice.
adele
Is Prokolin advance safe for dogs with food allergy?
We would advise checking with your vet as it will depend on what ingredients they are allergic to.
Mr P Allen
What size do I need for my 30kilo labrador
It is advised to give dogs between 15-30 kg, 5ml - twice daily. The 30ml or 60ml syringe would be most suitable.
Mr P Allen
What size do I need for my 30kilo labrador
| Feed your 30kg dog | 7ml | Twice daily. The 30ml or 60ml syringe would be suitable.
Melek Sasa
I bought 30 ml for dogs by mistake. Can I use it for my cats ? Is it safe ?
We would best recommend using the formula for cats.
Maurice Wilcox
The pro-kolin advanced 60ml only scales from 25kgs, what size dose for a 15kg spaniel.
Your 15kg dog will need a 15ml or 30ml syringe as the dose is 3ml twice daily (or 5ml if over 15kg). A 15ml should be enough if dosing at 3ml twice daily, this will last 2+1/2 days.
Marie
My cat doesn't like being held and having a syringe put in her mouth, it stresses us both out a lot, can this be added to her food instead?
Yes, this can be added directly to the food.
Marie and Daisy
My cat has been diagnosed with a sensitive tummy and has become allergic to regular cat food and biscuits so the vet advised me to totally change her diet which I've done and to give her cobalaplex to help her regain the weight she's lost and to help firm up her stools. This has been ongoing for about 5 months. I was wondering if Pro kolin would help her and if we can use it instead of the cobalaplex, alongside it or not at all? Ideally I would like to help her regain the weight she'd lost and firm up her stools and generally make her feel better. She's 14 and weighs aprox 1.9kg, she's always been small so it's really important for me to help her in any way I can.
Your advise would be very much appreciated. Thank you.
It is recommended to discuss this with the vet who advised to give Cobapalaplex. Pro Kolin and Cobalaplex do have different ingredients and there may be a specific reason your vet has advised one over the other.
MAS
How do you use the syringe for calculating the correct dose?
The syringe itself comes with volume measurements on it. You will need to move the wheel up these measurements to choose the correct dose, as in the image below. The packaging will contain further guidance on how this is done: